Daclatasvir

Daclatasvir is an antiviral medication used in combination with other drugs to treat chronic hepatitis C virus (HCV) infection. It works by inhibiting the NS5A protein, which is essential for viral replication.

Indications

-Treatment of chronic hepatitis C virus (HCV) infection -Used in combination with other antiviral medications for enhanced efficacy

Dosage

-Adults: Typically 60 mg once daily. Dosage may vary based on the specific combination therapy and patient condition. -Pediatric: Dosage for children must be determined by a healthcare provider based on individual needs.

Contra-Indications

-Hypersensitivity to Daclatasvir or any component of the formulation -Severe liver impairment or decompensated liver disease

Special Precautions

-Monitor liver function regularly -Assess potential drug interactions -Caution in patients with a history of liver disease

Side Effects

-Common: Fatigue, headache, nausea, diarrhea -Serious: Liver enzyme abnormalities, allergic reactions, rash

Drug Interactions

-May interact with other drugs metabolized by CYP3A4 (e.g., certain antiepileptics, HIV protease inhibitors) -Adjustments or monitoring may be needed when used with drugs affecting CYP3A4