ENTECAVIR

Indications

Hepatitis B

Dosage

Oral; 0.5mg to 1mg once daily.

Contra-Indications

HIV infection and hypersensitivity.

Special Precautions

Severe acute exacerbations of hepatitis B, Patients co-infected with HIV and HBV' lactic acidosis and hepatomegaly, renal impairment Paediatric: Safety below 16yrs not established. Pregnancy: Category C. Use if risk to fetus out weighs benefits. Lactation: Excreted in milk

Side Effects

Headache, fatigue, dizziness, nausea, hepatic impairment.

Drug Interactions

It is excreted by kidney so do not administer drugs which effect kidney function